Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs

RNA-binding proteins HuR and AUF1 bind to many common AU-rich target mRNAs and exert opposing influence on target mRNA stability, but the functional interactions between HuR and AUF1 have not been systematically studied. Here, using common target RNAs encoding p21 and cyclin D1, we provide evidence...

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Bibliographische Detailangaben
Hauptverfasser: Lal, Ashish, Mazan-Mamczarz, Krystyna, Kawai, Tomoko, Yang, Xiaoling, Martindale, Jennifer L, Gorospe, Myriam
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2004
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC514922/
https://ncbi.nlm.nih.gov/pubmed/15257295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600305
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