Influence of the RNA-Binding Protein HuR in pVHL-Regulated p53 Expression in Renal Carcinoma Cells

A recent analysis of gene expression in renal cell carcinoma cells led to the identification of mRNAs whose translation was dependent on the presence of the von Hippel-Lindau (VHL) tumor suppressor gene product, pVHL. Here, we investigate the finding that pVHL-expressing RCC cells (VHL(+)) exhibited...

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Autori principali: Galbán, Stefanie, Martindale, Jennifer L., Mazan-Mamczarz, Krystyna, de Silanes, Isabel López, Fan, Jinshui, Wang, Wengong, Decker, Jochen, Gorospe, Myriam
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC230328/
https://ncbi.nlm.nih.gov/pubmed/14517280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.20.7083-7095.2003
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