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Cleavage and proteasome-mediated degradation of the basal transcription factor TFIIA
The transcription factor TFIIA is encoded by two genes, TFIIAαβ and TFIIAγ. In higher eukaryotes, the TFIIAαβ is translated as a precursor and undergoes proteolytic cleavage; the regulation and biological implications of the cleavage have remained elusive. We determined by Edman degradation that the...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Nature Publishing Group
2004
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514921/ https://ncbi.nlm.nih.gov/pubmed/15257296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600304 |
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