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Preferential cleavage of chromatin-bound cohesin after targeted phosphorylation by Polo-like kinase

The final irreversible step in the duplication and dissemination of eukaryotic genomes takes place when sister chromatid pairs split and separate in anaphase. This is triggered by the protease separase that cleaves the Scc1 subunit of ‘cohesin', the protein complex responsible for holding siste...

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Detalhes bibliográficos
Main Authors: Hornig, Nadine C D, Uhlmann, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514920/
https://ncbi.nlm.nih.gov/pubmed/15241476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600303
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