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Polo-like kinase 1 as target for cancer therapy

Polo-like kinase 1 (Plk1) is an interesting molecule both as a biomarker and as a target for highly specific cancer therapy for several reasons. Firstly, it is over-expressed in many cancers and can serve as a biomarker to monitor treatment efficacy of Plk1 inhibitors. Furthermore, the Plk1 enzyme i...

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Hlavní autoři: Weiß, Lily, Efferth, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533518/
https://ncbi.nlm.nih.gov/pubmed/23227884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-1-38
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