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Targeting polo-like kinase 1 in acute myeloid leukemia
Polo-like kinase 1 (Plk1) plays a number of important roles in the passage of cells through mitosis. It is expressed at high levels in a variety of malignancies, including acute myeloid leukemia (AML). Inhibition of Plk1 results in cell cycle arrest and apoptosis, and has anti-tumor effects in pre-c...
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| Pubblicato in: | Ther Adv Hematol |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SAGE Publications
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365055/ https://ncbi.nlm.nih.gov/pubmed/25830015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620715571077 |
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