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Single Nucleotide Polymorphism–Based Validation of Exonic Splicing Enhancers

Because deleterious alleles arising from mutation are filtered by natural selection, mutations that create such alleles will be underrepresented in the set of common genetic variation existing in a population at any given time. Here, we describe an approach based on this idea called VERIFY (variant...

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書目詳細資料
Main Authors: Fairbrother, William G, Holste, Dirk, Burge, Christopher B, Sharp, Phillip A
格式: Artigo
語言:Inglês
出版: Public Library of Science 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC514884/
https://ncbi.nlm.nih.gov/pubmed/15340491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020268
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