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Variation in alternative splicing across human tissues

BACKGROUND: Alternative pre-mRNA splicing (AS) is widely used by higher eukaryotes to generate different protein isoforms in specific cell or tissue types. To compare AS events across human tissues, we analyzed the splicing patterns of genomically aligned expressed sequence tags (ESTs) derived from...

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Autori principali: Yeo, Gene, Holste, Dirk, Kreiman, Gabriel, Burge, Christopher B
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC545594/
https://ncbi.nlm.nih.gov/pubmed/15461793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-5-10-r74
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