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A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion
Innate immune signaling pathways contribute to the protection of host tissue when bacterially challenged. Colonic goblet cells are responsible for generating the two mucus layers that physically separate the luminal microbiota from the host epithelium. We report the identification of a ‘sentinel’ go...
Tallennettuna:
| Julkaisussa: | Science |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5148821/ https://ncbi.nlm.nih.gov/pubmed/27339979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf7419 |
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