Ebselen exerts antifungal activity by regulating glutathione (GSH) and reactive oxygen species (ROS) production in fungal cells

BACKGROUND: Ebselen, an organoselenium compound and a clinically safe molecule has been reported to possess potent antifungal activity, but its antifungal mechanism of action and in vivo antifungal activity remains unclear. METHODS: The antifungal effect of ebselen was tested against Candida albican...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biochim Biophys Acta
Autori principali: Thangamani, Shankar, Eldesouky, Hassan E., Mohammad, Haroon, Pascuzzi, Pete E., Avramova, Larisa, Hazbun, Tony R., Seleem, Mohamed N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148707/
https://ncbi.nlm.nih.gov/pubmed/27712973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.09.029
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi