Antitubercular activity of 1,2,3-triazolyl fatty acid derivatives

A collection of 1,2,3-triazoles unsaturated fatty acid mimics were efficiently synthesized by click chemistry. The 1,4-disubstituted analogs prepared covered different alkyl chain lengths and triazole positions. The compounds were subsequently tested against Mycobacterium tuberculosis, being most of...

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Vydáno v:Eur J Med Chem
Hlavní autoři: Ghiano, Diego G., de la Iglesia, Agustina, Liu, Nina, Tonge, Peter J., Morbidoni, Héctor R., Labadie, Guillermo R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148633/
https://ncbi.nlm.nih.gov/pubmed/27750201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.09.086
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