Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives

Two series of 6-(1,2,3-triazolyl)-2,3-dibenzyl-l-ascorbic acid derivatives with the hydroxyethylene (8a−8u) and ethylidene linkers (10c−10p) were synthesized and evaluated for their antiproliferative activity against seven malignant tumor cell lines and antiviral activity against a broad range of vi...

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Pubblicato in:Eur J Med Chem
Autori principali: Macan, Andrijana Meščić, Harej, Anja, Cazin, Ines, Klobučar, Marko, Stepanić, Višnja, Pavelić, Krešimir, Pavelić, Sandra Kraljević, Schols, Dominique, Snoeck, Robert, Andrei, Graciela, Raić-Malić, Silvana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Masson SAS. 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115614/
https://ncbi.nlm.nih.gov/pubmed/31586832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2019.111739
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