Mechanism of cargo-directed Atg8 conjugation during selective autophagy

Selective autophagy is mediated by cargo receptors that link the cargo to the isolation membrane via interactions with Atg8 proteins. Atg8 proteins are localized to the membrane in an ubiquitin-like conjugation reaction, but how this conjugation is coupled to the presence of the cargo is unclear. He...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fracchiolla, Dorotea, Sawa-Makarska, Justyna, Zens, Bettina, de Ruiter, Anita, Zaffagnini, Gabriele, Brezovich, Andrea, Romanov, Julia, Runggatscher, Kathrin, Kraft, Claudine, Zagrovic, Bojan, Martens, Sascha
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148612/
https://ncbi.nlm.nih.gov/pubmed/27879200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18544
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