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Using the Amino Acid Network to Modulate the Hydrolytic Activity of β-Glycosidases

The active site residues in GH1 β-glycosidases are compartmentalized into 3 functional regions, involved in catalysis or binding of glycone and aglycone motifs from substrate. However, it still remains unclear how residues outside the active site modulate the enzymatic activity. To tackle this quest...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tamaki, Fábio K., Souza, Diorge P., Souza, Valquiria P., Ikegami, Cecilia M., Farah, Chuck S., Marana, Sandro R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148593/
https://ncbi.nlm.nih.gov/pubmed/27936116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167978
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