Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion

BACKGROUND & AIMS: Developmental morphogens play an important role in coordinating the ductular reaction and portal fibrosis occurring in the setting of cholangiopathies. However, little is known about how membrane signaling events in ductular reactive cells (DRCs) are transduced into nuclear tr...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Jalan-Sakrikar, Nidhi, De Assuncao, Thiago M., Lu, Jie, Almada, Luciana L., Lomberk, Gwen, Fernandez-Zapico, Martin E., Urrutia, Raul, Huebert, Robert C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148157/
https://ncbi.nlm.nih.gov/pubmed/27936185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168266
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires