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Kinase Screening in Pichia pastoris Identified Promising Targets Involved in Cell Growth and Alcohol Oxidase 1 Promoter (P(AOX1)) Regulation

As one of the most commonly used eukaryotic recombinant protein expression systems, P. pastoris relies heavily on the AOX1 promoter (P(AOX1)), which is strongly induced by methanol but strictly repressed by glycerol and glucose. However, the complicated signaling pathways involved in P(AOX1) regulat...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Shen, Wei, Kong, Chuixing, Xue, Ying, Liu, Yiqi, Cai, Menghao, Zhang, Yuanxing, Jiang, Tianyi, Zhou, Xiangshan, Zhou, Mian
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147967/
https://ncbi.nlm.nih.gov/pubmed/27936065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167766
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