Kinase Screening in Pichia pastoris Identified Promising Targets Involved in Cell Growth and Alcohol Oxidase 1 Promoter (P(AOX1)) Regulation

As one of the most commonly used eukaryotic recombinant protein expression systems, P. pastoris relies heavily on the AOX1 promoter (P(AOX1)), which is strongly induced by methanol but strictly repressed by glycerol and glucose. However, the complicated signaling pathways involved in P(AOX1) regulat...

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Udgivet i:PLoS One
Main Authors: Shen, Wei, Kong, Chuixing, Xue, Ying, Liu, Yiqi, Cai, Menghao, Zhang, Yuanxing, Jiang, Tianyi, Zhou, Xiangshan, Zhou, Mian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147967/
https://ncbi.nlm.nih.gov/pubmed/27936065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167766
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