Mit1 Transcription Factor Mediates Methanol Signaling and Regulates the Alcohol Oxidase 1 (AOX1) Promoter in Pichia pastoris

The alcohol oxidase 1 (AOX1) promoter (P(AOX1)) of Pichia pastoris is the most powerful and commonly used promoter for driving protein expression. However, mechanisms regulating its transcriptional activity are unclear. Here, we identified a Zn(II)(2)Cys(6)-type methanol-induced transcription factor...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Wang, Xiaolong, Wang, Qi, Wang, Jinjia, Bai, Peng, Shi, Lei, Shen, Wei, Zhou, Mian, Zhou, Xiangshan, Zhang, Yuanxing, Cai, Menghao
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813576/
https://ncbi.nlm.nih.gov/pubmed/26828066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.692053
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