Mutation in Enterovirus 71 Capsid Protein VP1 Confers Resistance to the Inhibitory Effects of Pyridyl Imidazolidinone

Enterovirus 71 is one of the most important pathogens in the family of Picornaviridae that can cause severe complications in the postpoliovirus era, such as encephalitis, pulmonary edema, and even death. Pyridyl imidazolidinone is a novel class of potent and selective human enterovirus 71 inhibitor....

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Bibliografske podrobnosti
Main Authors: Shih, Shin-Ru, Tsai, Mun-Chung, Tseng, Sung-Nien, Won, Kuo-Fang, Shia, Kak-Shan, Li, Wen-Tai, Chern, Jyh-Haur, Chen, Guang-Wu, Lee, Chung-Chi, Lee, Yen-Chun, Peng, Kuan-Chang, Chao, Yu-Sheng
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC514779/
https://ncbi.nlm.nih.gov/pubmed/15328120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3523-3529.2004
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