Mutation in Enterovirus 71 Capsid Protein VP1 Confers Resistance to the Inhibitory Effects of Pyridyl Imidazolidinone

Enterovirus 71 is one of the most important pathogens in the family of Picornaviridae that can cause severe complications in the postpoliovirus era, such as encephalitis, pulmonary edema, and even death. Pyridyl imidazolidinone is a novel class of potent and selective human enterovirus 71 inhibitor....

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Dades bibliogràfiques
Autors principals: Shih, Shin-Ru, Tsai, Mun-Chung, Tseng, Sung-Nien, Won, Kuo-Fang, Shia, Kak-Shan, Li, Wen-Tai, Chern, Jyh-Haur, Chen, Guang-Wu, Lee, Chung-Chi, Lee, Yen-Chun, Peng, Kuan-Chang, Chao, Yu-Sheng
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514779/
https://ncbi.nlm.nih.gov/pubmed/15328120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3523-3529.2004
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