Mutation in Enterovirus 71 Capsid Protein VP1 Confers Resistance to the Inhibitory Effects of Pyridyl Imidazolidinone

Enterovirus 71 is one of the most important pathogens in the family of Picornaviridae that can cause severe complications in the postpoliovirus era, such as encephalitis, pulmonary edema, and even death. Pyridyl imidazolidinone is a novel class of potent and selective human enterovirus 71 inhibitor....

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Detalhes bibliográficos
Main Authors: Shih, Shin-Ru, Tsai, Mun-Chung, Tseng, Sung-Nien, Won, Kuo-Fang, Shia, Kak-Shan, Li, Wen-Tai, Chern, Jyh-Haur, Chen, Guang-Wu, Lee, Chung-Chi, Lee, Yen-Chun, Peng, Kuan-Chang, Chao, Yu-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514779/
https://ncbi.nlm.nih.gov/pubmed/15328120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3523-3529.2004
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