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A Stochastic Model of the Yeast Cell Cycle Reveals Roles for Feedback Regulation in Limiting Cellular Variability

The cell division cycle of eukaryotes is governed by a complex network of cyclin-dependent protein kinases (CDKs) and auxiliary proteins that govern CDK activities. The control system must function reliably in the context of molecular noise that is inevitable in tiny yeast cells, because mistakes in...

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發表在:PLoS Comput Biol
Main Authors: Barik, Debashis, Ball, David A., Peccoud, Jean, Tyson, John J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147779/
https://ncbi.nlm.nih.gov/pubmed/27935947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005230
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