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A Stochastic Model of the Yeast Cell Cycle Reveals Roles for Feedback Regulation in Limiting Cellular Variability

The cell division cycle of eukaryotes is governed by a complex network of cyclin-dependent protein kinases (CDKs) and auxiliary proteins that govern CDK activities. The control system must function reliably in the context of molecular noise that is inevitable in tiny yeast cells, because mistakes in...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Barik, Debashis, Ball, David A., Peccoud, Jean, Tyson, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147779/
https://ncbi.nlm.nih.gov/pubmed/27935947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005230
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