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A Stochastic Model of the Yeast Cell Cycle Reveals Roles for Feedback Regulation in Limiting Cellular Variability

The cell division cycle of eukaryotes is governed by a complex network of cyclin-dependent protein kinases (CDKs) and auxiliary proteins that govern CDK activities. The control system must function reliably in the context of molecular noise that is inevitable in tiny yeast cells, because mistakes in...

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Publicado en:PLoS Comput Biol
Main Authors: Barik, Debashis, Ball, David A., Peccoud, Jean, Tyson, John J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147779/
https://ncbi.nlm.nih.gov/pubmed/27935947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005230
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