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Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens

An important focus in vaccine research is the design of vaccine vectors with low seroprevalence and high immunogenicity. Replication-incompetent lymphocytic choriomeningitis virus (rLCMV) vectors do not elicit vector-neutralizing antibody responses, and homologous prime-boost regimens with rLCMV vec...

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Bibliographic Details
Published in:Vaccine
Main Authors: MacMaster, Pablo Penaloza, Shields, Jennifer L., Alayo, Quazim A., Cabral, Crystal, Jimenez, Jessica, Mondesir, Jade, Chandrashekar, Abishek, Cabral, Joseph M., Lim, Matthew, Iampietro, M. Justin, Provine, Nicholas M., Bricault, Christine A., Seaman, Michael, Orlinger, Klaus, Aspoeck, Andreas, Fuhrmann, Gerhard, Lilja, Anders, Monath, Thomas, Mangeat, Bastien, Pinschewer, Daniel D., Barouch, Dan H.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147735/
https://ncbi.nlm.nih.gov/pubmed/27899229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.11.063
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