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Additive Protection against Congenital Cytomegalovirus Conferred by Combined Glycoprotein B/pp65 Vaccination Using a Lymphocytic Choriomeningitis Virus Vector

Subunit vaccines for prevention of congenital cytomegalovirus (CMV) infection based on glycoprotein B (gB) and pp65 are in clinical trials, but it is unclear whether simultaneous vaccination with both antigens enhances protection. We undertook evaluation of a novel bivalent vaccine based on nonrepli...

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Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: Schleiss, Mark R., Berka, Ursula, Watson, Elizabeth, Aistleithner, Mario, Kiefmann, Bettina, Mangeat, Bastien, Swanson, Elizabeth C., Gillis, Peter A., Hernandez-Alvarado, Nelmary, Fernández-Alarcón, Claudia, Zabeli, Jason C., Pinschewer, Daniel D., Lilja, Anders E., Schwendinger, Michael, Guirakhoo, Farshad, Monath, Thomas P., Orlinger, Klaus K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216435/
https://ncbi.nlm.nih.gov/pubmed/27795301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00300-16
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