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Distribution of Amphotericin B-Arabinogalactan Conjugate in Mouse Tissue and Its Therapeutic Efficacy against Murine Aspergillosis

The pharmacokinetic characteristics and tissue distribution of a novel water-soluble, nontoxic amphotericin B-arabinogalactan (AMB-AG) conjugate exhibited distinct differences from those of micellar and liposomal amphotericin B formulations. These differences included extended persistence of drug in...

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Detalles Bibliográficos
Main Authors: Falk, Rama, Grunwald, Jacob, Hoffman, Amnon, Domb, Abraham J., Polacheck, Itzhack
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC514765/
https://ncbi.nlm.nih.gov/pubmed/15328139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3606-3609.2004
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