Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons

Astrocytes are critical in synapse development, and their dysfunction in crucial developmental stages leads to serious neurodevelopmental diseases, including seizures and epilepsy. Immune challenges not only affect brain development, but also promote seizure generation and epileptogenesis, implying...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Shen, Yi, Qin, Huaping, Chen, Juan, Mou, Lingyan, He, Yang, Yan, Yixiu, Zhou, Hang, Lv, Ya, Chen, Zhong, Wang, Junlu, Zhou, Yu-Dong
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2016
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147000/
https://ncbi.nlm.nih.gov/pubmed/27920126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201605046
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