Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons

Astrocytes are critical in synapse development, and their dysfunction in crucial developmental stages leads to serious neurodevelopmental diseases, including seizures and epilepsy. Immune challenges not only affect brain development, but also promote seizure generation and epileptogenesis, implying...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Shen, Yi, Qin, Huaping, Chen, Juan, Mou, Lingyan, He, Yang, Yan, Yixiu, Zhou, Hang, Lv, Ya, Chen, Zhong, Wang, Junlu, Zhou, Yu-Dong
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2016
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147000/
https://ncbi.nlm.nih.gov/pubmed/27920126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201605046
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