Increasing the Chemical‐Shift Dispersion of Unstructured Proteins with a Covalent Lanthanide Shift Reagent

The study of intrinsically disordered proteins (IDPs) by NMR often suffers from highly overlapped resonances that prevent unambiguous chemical‐shift assignments, and data analysis that relies on well‐separated resonances. We present a covalent paramagnetic lanthanide‐binding tag (LBT) for increasing...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Göbl, Christoph, Resch, Moritz, Strickland, Madeleine, Hartlmüller, Christoph, Viertler, Martin, Tjandra, Nico, Madl, Tobias
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146990/
https://ncbi.nlm.nih.gov/pubmed/27763708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201607261
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky