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Prediction of Protein Structure Using Surface Accessibility Data

An approach to the de novo structure prediction of proteins is described that relies on surface accessibility data from NMR paramagnetic relaxation enhancements by a soluble paramagnetic compound (sPRE). This method exploits the distance‐to‐surface information encoded in the sPRE data in the chemica...

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Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Hartlmüller, Christoph, Göbl, Christoph, Madl, Tobias
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026166/
https://ncbi.nlm.nih.gov/pubmed/27560616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201604788
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