Loading...

Increasing the Chemical‐Shift Dispersion of Unstructured Proteins with a Covalent Lanthanide Shift Reagent

The study of intrinsically disordered proteins (IDPs) by NMR often suffers from highly overlapped resonances that prevent unambiguous chemical‐shift assignments, and data analysis that relies on well‐separated resonances. We present a covalent paramagnetic lanthanide‐binding tag (LBT) for increasing...

Full description

Saved in:
Bibliographic Details
Published in:Angew Chem Int Ed Engl
Main Authors: Göbl, Christoph, Resch, Moritz, Strickland, Madeleine, Hartlmüller, Christoph, Viertler, Martin, Tjandra, Nico, Madl, Tobias
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146990/
https://ncbi.nlm.nih.gov/pubmed/27763708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201607261
Tags: Add Tag
No Tags, Be the first to tag this record!