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Mouse-based genetic modeling and analysis of Down syndrome
INTRODUCTION: Down syndrome (DS), caused by human trisomy 21 (Ts21), can be considered as a prototypical model for understanding the effects of chromosomal aneuploidies in other diseases. Human chromosome 21 (Hsa21) is syntenically conserved with three regions in the mouse genome. SOURCES OF DATA: A...
Enregistré dans:
| Publié dans: | Br Med Bull |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5146682/ https://ncbi.nlm.nih.gov/pubmed/27789459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bmb/ldw040 |
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