Mouse-based genetic modeling and analysis of Down syndrome

INTRODUCTION: Down syndrome (DS), caused by human trisomy 21 (Ts21), can be considered as a prototypical model for understanding the effects of chromosomal aneuploidies in other diseases. Human chromosome 21 (Hsa21) is syntenically conserved with three regions in the mouse genome. SOURCES OF DATA: A...

Full description

Saved in:
Bibliographic Details
Published in:Br Med Bull
Main Authors: Xing, Zhuo, Li, Yichen, Pao, Annie, Bennett, Abigail S., Tycko, Benjamin, Mobley, William C., Yu, Y. Eugene
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Invited Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146682/
https://ncbi.nlm.nih.gov/pubmed/27789459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bmb/ldw040
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items