Major genetic marker of nidoviruses encodes a replicative endoribonuclease

Coronaviruses are important pathogens that cause acute respiratory diseases in humans. Replication of the ≈30-kb positive-strand RNA genome of coronaviruses and discontinuous synthesis of an extensive set of subgenome-length RNAs (transcription) are mediated by the replicase-transcriptase, a barely...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Ivanov, Konstantin A., Hertzig, Tobias, Rozanov, Mikhail, Bayer, Sonja, Thiel, Volker, Gorbalenya, Alexander E., Ziebuhr, John
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514660/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15304651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403127101
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