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The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity

Hepatic immunobiology is paradoxical: although the liver possesses unusual tolerogenic properties, it is also the site of effective immune responses against multiple pathogens and subject to immune-mediated pathology. The mechanisms underlying this dichotomy remain unclear. Following previous work d...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Bowen, David G., Zen, Monica, Holz, Lauren, Davis, Thomas, McCaughan, Geoffrey W., Bertolino, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514586/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15343389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI21593
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