Intrahepatic murine CD8 T cell activation associates with a distinct phenotype leading to Bim-dependent death

BACKGROUND AND AIMS: Chronic infections by hepatotropic viruses such as hepatitis B and C are generally associated with an impaired CD8 T cell immune response that is unable to clear the virus. The liver is increasingly recognised as an alternative site where primary activation of CD8 T cells takes...

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Bibliografiska uppgifter
Huvudupphovsmän: Holz, Lauren E, Benseler, Volker, Bowen, David G, Bouillet, Philippe, Strasser, Andreas, O'Reilly, Lorraine, d'Avigdor, William, Bishop, Alex G, McCaughan, Geoffrey W, Bertolino, Patrick
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956118/
https://ncbi.nlm.nih.gov/pubmed/18619445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.05.078
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