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Tetrodotoxin-sensitive Ca(2+) currents, but no T-type currents in normal, hypertrophied and failing mouse cardiomyocytes

AIMS: To obtain functional evidence that I(Ca,T) is involved in the pathogenesis of cardiac hypertrophy and heart failure. We unexpectedly identified I(Ca(TTX)) rather than I(Ca,T), therefore, we adjusted our aim to encompass these findings. METHODS AND RESULTS: We investigated 1) Ca(v)3.1 (α(1G)) t...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol
Main Authors: Bodi, Ilona, Nakayama, Hiroyuki, Schwartz, Arnold
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145783/
https://ncbi.nlm.nih.gov/pubmed/27617699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000432
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