A dual function fusion protein of Herpes simplex virus type 1 thymidine kinase and firefly luciferase for noninvasive in vivo imaging of gene therapy in malignant glioma

BACKGROUND: Suicide gene therapy employing the prodrug activating system Herpes simplex virus type 1 thymidine kinase (HSV-TK)/ ganciclovir (GCV) has proven to be effective in killing experimental brain tumors. In contrast, glioma patients treated with HSV-TK/ GCV did not show significant treatment...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genet Vaccines Ther
Egile Nagusiak: Söling, Ariane, Theiß, Christian, Jungmichel, Stephanie, Rainov, Nikolai G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2004
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514571/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15294018/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1479-0556-2-7
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