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Genetic Incorporation of a Herpes Simplex Virus Type 1 Thymidine Kinase and Firefly Luciferase Fusion into the Adenovirus Protein IX for Functional Display on the Virion

An advantage of the adenoviral vector is its molecular flexibility, which allows for vector tropism modifications for the purpose of cell targeting. In addition to targeting ligands, the capacity to incorporate heterologous peptides has allowed capsid incorporation of other functionalities. We have...

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Main Authors: Matthews, Qiana L., Sibley, Don A., Wu, Hongju, Li, Jing, Stoff-Khalili, Mariam A., Waehler, Reinhard, Mathis, J. Michael, Curiel, David T.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781529/
https://ncbi.nlm.nih.gov/pubmed/17150163
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