BRUTON’S TYROSINE KINASE INHIBITORS PREVENT THERAPEUTIC ESCAPE IN BREAST CANCER CELLS

We have reported that a novel isoform of BTK (BTK-C) expressed in breast cancer protects these cells from apoptosis. In this study, we show that recently developed inhibitors of BTK, such as ibrutinib (PCI-32765), AVL-292 and CGI-1746, reduce breast cancer cell survival and prevent drug resistant cl...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer Ther
Asıl Yazarlar: Wang, Xianhui, Wong, Jason, Sevinsky, Christopher J, Kokabee, Leila, Khan, Faiza, Sun, Yan, Conklin, Douglas S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145257/
https://ncbi.nlm.nih.gov/pubmed/27256378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0813
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