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Bruton's tyrosine kinase is a potential therapeutic target in prostate cancer

Bruton's tyrosine kinase (BTK) is a non-receptor tyrosine kinase that has mainly been studied in haematopoietic cells. We have investigated whether BTK is a potential therapeutic target in prostate cancer. We find that BTK is expressed in prostate cells, with the alternate BTK-C isoform predomi...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Kokabee, Leila, Wang, Xianhui, Sevinsky, Christopher J, Wang, Wei Lin Winnie, Cheu, Lindsay, Chittur, Sridar V, Karimipoor, Morteza, Tenniswood, Martin, Conklin, Douglas S
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846115/
https://ncbi.nlm.nih.gov/pubmed/26383180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1078023
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