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True reversal of Mu integration

We describe a high-temperature (75°C) transition in the Mu integration complex that causes efficient and true reversal of the integration reaction. A second reversal pathway, first described as ‘foldback' reversal for the HIV integrase, was also observed upon disassembly/reassembly of the Mu complex...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Au, T K, Pathania, Shailja, Harshey, Rasika M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15282550/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600344
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