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True reversal of Mu integration

We describe a high-temperature (75°C) transition in the Mu integration complex that causes efficient and true reversal of the integration reaction. A second reversal pathway, first described as ‘foldback' reversal for the HIV integrase, was also observed upon disassembly/reassembly of the Mu co...

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Detalhes bibliográficos
Main Authors: Au, T K, Pathania, Shailja, Harshey, Rasika M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514517/
https://ncbi.nlm.nih.gov/pubmed/15282550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600344
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