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True reversal of Mu integration

We describe a high-temperature (75°C) transition in the Mu integration complex that causes efficient and true reversal of the integration reaction. A second reversal pathway, first described as ‘foldback' reversal for the HIV integrase, was also observed upon disassembly/reassembly of the Mu co...

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Détails bibliographiques
Auteurs principaux: Au, T K, Pathania, Shailja, Harshey, Rasika M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC514517/
https://ncbi.nlm.nih.gov/pubmed/15282550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600344
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