Development of RNA-FISH Assay for Detection of Oncogenic FGFR3-TACC3 Fusion Genes in FFPE Samples

INTRODUCTION AND OBJECTIVES: Oncogenic FGFR3-TACC3 fusions and FGFR3 mutations are target candidates for small molecule inhibitors in bladder cancer (BC). Because FGFR3 and TACC3 genes are located very closely on chromosome 4p16.3, detection of the fusion by DNA-FISH (fluorescent in situ hybridizati...

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Vydáno v:PLoS One
Hlavní autoři: Kurobe, Masahiro, Kojima, Takahiro, Nishimura, Kouichi, Kandori, Shuya, Kawahara, Takashi, Yoshino, Takayuki, Ueno, Satoshi, Iizumi, Yuichi, Mitsuzuka, Koji, Arai, Yoichi, Tsuruta, Hiroshi, Habuchi, Tomonori, Kobayashi, Takashi, Matsui, Yoshiyuki, Ogawa, Osamu, Sugimoto, Mikio, Kakehi, Yoshiyuki, Nagumo, Yoshiyuki, Tsutsumi, Masakazu, Oikawa, Takehiro, Kikuchi, Koji, Nishiyama, Hiroyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145148/
https://ncbi.nlm.nih.gov/pubmed/27930669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165109
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