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Development of RNA-FISH Assay for Detection of Oncogenic FGFR3-TACC3 Fusion Genes in FFPE Samples

INTRODUCTION AND OBJECTIVES: Oncogenic FGFR3-TACC3 fusions and FGFR3 mutations are target candidates for small molecule inhibitors in bladder cancer (BC). Because FGFR3 and TACC3 genes are located very closely on chromosome 4p16.3, detection of the fusion by DNA-FISH (fluorescent in situ hybridizati...

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Publicado en:PLoS One
Autores principales: Kurobe, Masahiro, Kojima, Takahiro, Nishimura, Kouichi, Kandori, Shuya, Kawahara, Takashi, Yoshino, Takayuki, Ueno, Satoshi, Iizumi, Yuichi, Mitsuzuka, Koji, Arai, Yoichi, Tsuruta, Hiroshi, Habuchi, Tomonori, Kobayashi, Takashi, Matsui, Yoshiyuki, Ogawa, Osamu, Sugimoto, Mikio, Kakehi, Yoshiyuki, Nagumo, Yoshiyuki, Tsutsumi, Masakazu, Oikawa, Takehiro, Kikuchi, Koji, Nishiyama, Hiroyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145148/
https://ncbi.nlm.nih.gov/pubmed/27930669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165109
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