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Ku Binding on Telomeres Occurs at Sites Distal from the Physical Chromosome Ends
The Ku complex binds non-specifically to DNA breaks and ensures repair via NHEJ. However, Ku is also known to bind directly to telomeric DNA ends and its presence there is associated with telomere capping, but avoiding NHEJ. How the complex discriminates between a DNA break and a telomeric extremity...
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| Gepubliceerd in: | PLoS Genet |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5145143/ https://ncbi.nlm.nih.gov/pubmed/27930670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006479 |
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