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Maintenance of Double-Stranded Telomeric Repeats as the Critical Determinant for Cell Viability in Yeast Cells Lacking Ku

The Saccharomyces cerevisiae Ku complex, while important for nonhomologous DNA end joining, is also necessary for maintaining wild-type telomere length and a normal chromosomal DNA end structure. Yeast cells lacking Ku can grow at 23°C but are unable to do so at elevated temperatures due to an activ...

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Bibliographic Details
Main Authors: Gravel, Serge, Wellinger, Raymund J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133694/
https://ncbi.nlm.nih.gov/pubmed/11884605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2182-2193.2002
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