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Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis
Phosphorylation on certain Ser/Thr-Pro motifs is a major oncogenic mechanism. The conformation and function of phosphorylated Ser/Thr-Pro motifs are further regulated by the prolyl isomerase Pin1. Pin1 is prevalently overexpressed in human cancers and implicated in oncogenesis. However, the role of...
Enregistré dans:
| Publié dans: | EMBO J |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514501/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15257284/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600323 |
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